Whole blood

Ideal matrix for most chemicals because it is in contact with the whole organism and in equilibrium with the organs and tissues in those chemicals are being accumulated.
Whole blood consists of several compartments; essential and accidental substances are differently distributed in single compartments. This is true for hydrophilic and lipophilic substance classes. Depending on distribution of a substance between blood plasma and cell-compartment of the blood must be decided whether analyses in whole blood or blood plasma make sense. Therefore, collecting whole blood is suitable to reflect the total exposure to pollutants.
Guideline for Sampling and Sample Processing Whole Blood and Blood Plasma (2015) - IBMT
Richtlinie zur Probenahme und Probenbearbeitung Vollblut und Blutplasma (2011) - UKM
Recommended analysis examples
Search data
Sampling area
Sampling sites (humans) | 4 university cities as sampling areas. |
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Analytes
Metals | Eighty percent of all elements on earth are metals |
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Sampling period
1981 - 2017
Extended information
Literature
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The Environmental Specimen Bank for Human Tissues as part of the German Environmental Specimen Bank
Wiesmüller, G.A.; Eckard, R; Dobler, L.; Günsel, A.; Oganowski, M.; Schröter-Kermani, C.; Schlüter, C.; Gies, A.; Kemper, F. H.
International Journal of Hygiene and Environmental Health 210 (2007), 3-4, 299-305, 2007