Blood plasma
Ideal matrix for most chemicals because it is in contact with the whole organism and in equilibrium with the organs and tissues in that chemicals are being accumulated
Blood plasma, a compartment of whole blood without cellular components, is the most important body fluid in clinical diagnostics. Essential trace and bulk elements are homeostatically regulated. Because of its lipid content, blood plasma can be used for concentration analysis of organic lipophilic xenobiotics. Depending on distribution of a substance between blood plasma and cell-compartment of the blood must be decided whether analyses in whole blood or blood plasma make sense.
Richtlinie zur Probenahme und Probenbearbeitung Vollblut und Blutplasma
Recommended analysis examples
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Sampling area
| Sampling sites (humans) | 4 university cities as sampling areas. |
|---|
Analytes
| Metals | Eighty percent of all elements on earth are metals |
|---|---|
| Nonmetals | Only eighteen elements in the periodic table |
| Chlorohydrocarbons | Group of organic compounds with at least one covalently bonded chlorine atom |
| Supplementary parameters | Additional information for the interpretation of contamination data |
Sampling period
1984 - 2010
Extended information
Literature
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The Environmental Specimen Bank for Human Tissues as part of the German Environmental Specimen Bank
Gerhard A. Wiesmüller, Rolf Eckard, Lenz Dobler, Andreas Günsel, Marek Oganowski, Christa Schröter-Kermani, Christoph Schlüter, Andreas Gies, Fritz H. Kemper
(2007) Int. J. Hyg. Environ.-Health 210, 299-305, 2007