Di-n-butyl phthalate
Short-chain phthalate registered as auxiliary for pharmaceutical products that have to be administered encapsulated to resist gastric juice
Dibutyl phthalate is a plasticizer with coagulating properties which is applied for instance in polyacrylate plastics and poly acetate dispersions. In combination with other plasticizers it is used as gellant in processing of so-called plastisols.
DBP is present e.g. in floor coverings, adhesives, nitrocellulose lacquers, gellants, and body care products like hair sprays, deodorants and perfumes. It is a good solvent for pesticides and oil soluble paints. Furthermore, DBP is used for encapsulation of drugs to resist gastric juice.
Due to its wide use, DBP is ubiquitous in the environment. It is, however, degraded relatively fast.
DBP is suspected to act as endocrine disruptor and to be toxic on reproduction and development.
It is very toxic for aquatic organisms.
The use of DPB in cosmetics, childcare articles and toys is banned in the EU.
For the Environmental Specimen Bank not the parent compound DBP itself is analysed in human specimens but its major metabolites.
Search data
Substances
| MnBP | Mono-n-butyl phthalate is the primary metabolite of DnBP resulting from the elimination of one butyl group. |
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Specimen
| Students | Student groups with an even number of female and male students at the age of 20 to 29. |
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Sampling area
| Sampling sites (humans) | 4 university cities as sampling areas. |
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Sampling period
1988 - 2008